Research Article
Transplantation of Human Amniotic Membrane over the Liver Surface Reduces Hepatic Fibrosis in a Cholestatic Model in Young Rats
| | Sham () | 2nd PO week () | 4th PO week () | 6th PO week () |
| | Albumin (g/dL) | 2.5 ± 0 | BDL: 2.4 ± 0.37
BDL + AM: 2.85 ± 0.07 | BDL: 1.88 ± 0.5
BDL + AM: 2.9 ± 0† | BDL: 1.99 ± 0.17
BDL + AM: 3.33 ± 0.36‡† |
| | ALT (U/L) | 70 ± 7.07 | BDL: 79.75 ± 17.99
BDL + AM: 106 ± 0 | BDL: 124.6 ± 58.8
BDL + AM: 76 ± 7.07 | BDL: 79 ± 46.16
BDL + AM: 56.71 ± 35.5 |
| | Alkaline phosphatase (U/L) | 573 ± 99 | BDL: 420 ± 84
BDL + AM: 324 ± 0 | BDL: 635.6 ± 197.53
BDL + AM: 419 ± 56.57 | BDL: 421 ± 172.52
BDL + AM: 278 ± 171 |
| | GGT (U/L) | 0 ± 0 | BDL: 24.75 ± 28.93
BDL + AM: 79 ± 0 | BDL: 35.8 ± 21.29
BDL + AM: 13.5 ± 19.09 | BDL: 33 ± 27.4
BDL + AM: 1.86 ± 3.49†† |
| | Bilirubin (mg/dL) | 0.1 ± 0 | BDL: 2.73 ± 2.86
BDL + AM: 10.7 ± 5.23 | BDL: 2.84 ± 1.68
BDL + AM: 2.65 ± 3.61 | BDL: 4.23 ± 1.12
BDL + AM: 2.39 ± 2.50 |
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ALT: alanine transaminase; GGT: gamma-glutamyl transpeptidase; PO: postoperative. BDL versus sham. BDL + AM versus sham. BDL versus BDL + AM. BDL versus BDL + AM. |
