Research Article
Mesenchymal Stem Cells in Oriented PLGA/ACECM Composite Scaffolds Enhance Structure-Specific Regeneration of Hyaline Cartilage in a Rabbit Model
Table 2
International Cartilage Repair Society Macroscopic Evaluation of Cartilage Repair.
| Cartilage repair assessment ICRS | Points |
| Degree of defect repair | | In level with surrounding cartilage | 4 | 75% repair of defect depth | 3 | 50% repair of defect depth | 2 | 25% repair of defect depth | 1 | 0% repair of defect depth | 0 | Integration to border zone | | Complete integration with surrounding cartilage | 4 | Demarcating border < 1 mm | 3 | 3/4th of graft integrated, 1/4th with a notable border > 1 mm width | 2 | 1/2 of graft integrated with surrounding cartilage, 1/2 with a notable border > 1 mm | 1 | From no contact to 1/4th of graft integrated with surrounding cartilage | 0 | Macroscopic appearance | | Intact smooth surface | 4 | Fibrillated surface | 3 | Small, scattered fissures or cracks | 2 | Several small or few but large fissures | 1 | Total degeneration of grafted area | 0 | Overall repair assessment | | Grade I: normal | 12 | Grade II: nearly normal | 11–8 | Grade III: abnormal | 7–4 | Grade IV: severely abnormal | 3–1 |
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ICRS: International Cartilage Repair Society.
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