TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton

Table 1

Osteogenesis- and adipogenesis-related genes, from the most enriched pathways, that are upregulated in TGFβ1-treated cells.

Endochondral ossification	Actin cytoskeleton	Focal adhesion	TGFβ signaling	MAPK signaling	Adipogenesis
VEGFA	FGF2	COL11A1	SMURF1	MAPK8	FOXO1A
ADAMTS4	FGFR1	COL3A1	MAPK8	NGFB	TRIB3
PLAT4	TMSB4X	COL4A1	SKP1	PDGFRB	PCK2
COL10A1	GNA13	COL4A2	NEDD9	RASA2	EGR2
TGFB2	PDGFA	COL4A4	ETS1	SOS2	DDIT3
PTHrP	FGF1	COL5A1	KLF11	KRAS	GADD45A
FGF2	ENAH	COL5A2	ATF3	MRAS	GADD45B
C4ST1	MSN	COL1A1	FOSB	NF1	HIF1A
FGFR1	GSN	LAMC2	SKIL	RAP1B	IRS1
PDGFRB	PDGFRB	THBS2	SMURF1	DUSP1	MEF2D
COL1	KRAS	CAV2	ZFYVE16	DDIT3	FAS
	MRAS	ARHGAP5		HSPB1	SPOCK
	SOS2	PTEN		IL1A
		AKT3		FAS
		PDGFA		TGFB2
		PDGFC		MAP313
		PGF		ZAK
		ITGA2		AKT3
		PDGFRB		MAP3K8
		RAP1B		GADD45A
		MAPK8