Tissue Engineering of Large Full-Size Meniscus Defects by a Polyurethane Scaffold: Accelerated Regeneration by Mesenchymal Stromal Cells

Figure 8

Left: microscopic view on transversal cut meniscus sections; CD 31 immunohistochemistry staining for the evaluation of vessel ingrowth. Vascular endothelial cells are stained black. The polyurethane scaffold (a) is completely surrounded by native meniscus tissue (b). Vascular endothelial cells are stained black and are shown by the vessels cuts (c), which were found in the peripheral as well as central parts of the scaffolds; benchmark for the left picture: . Right: microscopica view, CD 31 immunohistochemistry staining for the evaluation of vessel ingrowth. Vascular endothelial cells are stained black. (a) demonstrates the polyurethane scaffold, and (b) presents examples of vessel cuts; benchmark for the right picture: . Both pictures refer to MSC-loaded scaffold group after 6 weeks.