The Human Skin-Derived Precursors for Regenerative Medicine: Current State, Challenges, and Perspectives

Table 2

Summary of the relevant markers expressed by hSKPs.

Category	Markers	Ref.
Neural crest stem cells or neural system-related markers	Nestin, p75NTR, Pax3, Snail, Slug, Msx1, Twist, Lamin A/C, Dermo-1, Musashi, Sca-1, Sox9, Sox10, S100β	[5, 6, 19, 21, 25–27]
Mesenchymal or dermal cell-related markers	Fibronectin, vimentin, versican, Collagen III, αSMA	[4–6, 27, 28]
Embryonic stem cell-related markers	Sox2, Oct4, TG30, Nanog	[4, 25]
Endothelial, perivascular, or stromal cell-related markers	CD90, CD95, CD105, CD146	[19, 20]
Costimulatory molecule-related markers	CD40	[19]
Cell adhesion molecule-related markers	CD29, CD 44, CD49e, CD 54, CD166	[19]
Immunoregulatory molecule-related markers	CD73, HO-1	[19]
Human leukocyte antigen-related markers	HLA-ABC, intracellular HLA-G	[19]
Oncogenesis and development-related markers	Wnt-5a	[21]
Cellular proliferation-related markers	Ki67	[29]

αSMA: α smooth muscle actin; HLA: human leukocyte antigen; NTR: neurotrophin receptor.