Antiarrhythmic Effects of Carvedilol and Flecainide in Cardiomyocytes Derived from Catecholaminergic Polymorphic Ventricular Tachycardia Patients

Figure 2

Schematic presentation of RYR2 amino acid sequence and the localization of the studied mutations in it. Mutations in RYR2 are enriched into four clusters (1–4). Modified from [11].