Research Article
Antiarrhythmic Effects of Carvedilol and Flecainide in Cardiomyocytes Derived from Catecholaminergic Polymorphic Ventricular Tachycardia Patients
Figure 5
Parameters of the Ca2+ traces under each condition. (a) The upper row represents carvedilol data, and (b) the lower row represents flecainide data. ΔF/F0: Ca2+ peak amplitude; duration: Ca2+ peak duration; half-width: duration at half-maximum amplitude; frequency: the beating frequency of CMs. Data is shown as averages. BL = baseline; Adr = 1 μM adrenaline; CAR = 0.25 μM carvedilol; FLE = 10 μM flecainide. Statistical significance (). Error bars represent standard error of the mean (SEM).
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