Research Article
Antiarrhythmic Effects of Carvedilol and Flecainide in Cardiomyocytes Derived from Catecholaminergic Polymorphic Ventricular Tachycardia Patients
Table 1
Incidence of each calcium abnormality type in all CPVT CMs after adrenaline stimulation and the percentages of these arrhythmias abolished by either carvedilol or flecainide.
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MP, LP, and IP type of abnormal transients were abolished quite well by both drugs, while flecainide was superior in abolishing AL-type abnormalities. Incidence of LP and IP abnormalities was, however, low in CPVT CMs; therefore, conclusions should be made with caution. |