Mathematical Modeling Reveals the Role of Hypoxia in the Promotion of Human Mesenchymal Stem Cell Long-Term Expansion

Table 1

Model parameter values for normoxic and hypoxic conditions fitted from MSC expansion data collected in experiment A. : net expansion rate; : death rate of nondividing cells; , , and are the upper bound, the steepness, and the midpoint time of the logistic state transition rate , respectively.

Parameter	Normoxia	Hypoxia
(day^−1)	0.3472	0.3505
(day^−1)	0.0133	0.0183
(day^−1)	0.3588	0.3967
	0.3169	0.3944
(day)	47.3494	72.3664