Different Chondrogenic Potential among Human Induced Pluripotent Stem Cells from Diverse Origin Primary Cells

<div>Gene expression in chondrogenic pellets. The expression of transcriptional activators or early chondrogenesis markers (a) SOX9, (b) SOX5, and (c) SOX6 was confirmed. The expression of matrix proteins, (d) aggrecan (ACAN), (e) collagen type II (COL2A1), and lubricin (PRG4) was confirmed. Also, hypertrophy or fibrotic markers such as (g) collagen type I (COL1A1), (h) collagen type X (COL10A1), and (i) RUNX2 was confirmed as well. 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Stem Cells International

fig4

Figure 4

Figure 4: Different Chondrogenic Potential among Human Induced Pluripotent Stem Cells from Diverse Origin Primary Cells 