Human Bone Marrow Mesenchymal Stem Cells Promote Gastric Cancer Growth via Regulating c-Myc

Figure 3

Effect of hBM-MSC-CM on cell cycle progression and apoptosis in gastric cancer cells. (a) hBM-MSC-CM + JQ1 induced a G1 arrest compared with the hBM-MSC-CM group; the changes in cell cycle distribution were not significant after three experiments. (b) Western blot analysis of cyclin-D1 expression in hBM-MSC-CM + JQ1-treated MGC-803 cells. (c) Western blot analysis of Bcl-2 and Bax expression in hBM-MSC-CM + JQ1-treated MGC-803 cells.

(a)

(b)

(c)