Generation and Applications of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells

Figure 2

iMSC-based disease modeling and drug discovery of FOP. iMSCs generated from FOP patient-derived iPSC clones (FOP-iMSC) and gene-corrected (rescued) iPSC clones (resFOP-iPSC) could be applied to in vitro disease modeling, drug screening, and in vivo drug efficacy evaluation.