Fasudil Promotes BMSC Migration via Activating the MAPK Signaling Pathway and Application in a Model of Spinal Cord Injury

<div>FAS induces BMSC migration in vitro. (a) Scratch wound healing assay of BMSCs treated with 3, 10, and 30 <i>μ</i>M FAS. Phase contrast images were captured at 0, 12, and 24 h after the scratch. (b) Data quantified from the experiment shown in (a). Three random fields were selected from each group, and the rate of wound closure was measured using ImageJ software. (c) Analysis of FAS treatment on BMSCs by Transwell migration assay. Phase contrast images of migrated cells taken 24 h later. The result are shown as the mean value of 5 random fields from each insert. 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Stem Cells International

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Figure 3

Figure 3: Fasudil Promotes BMSC Migration via Activating the MAPK Signaling Pathway and Application in a Model of Spinal Cord Injury 