Luteolin-7-glucoside Promotes Human Epidermal Stem Cell Proliferation by Upregulating β-Catenin, c-Myc, and Cyclin Expression
Luteolin-7-glucoside promotes EpSC proliferation in organotypic skin. Human skin explants cultured with or without 1 μM luteolin-7-glucoside (L7G) for 2 and 5 days were examined for histology by HE staining and α6 integrin-positive, β1 integrin-positive, and proliferative cells by immunohistochemical staining. (a) Representative images. (b) Quantitative data of HE staining and immunohistochemical staining. ; compared with untreated skin explants.
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