Research Article
Isolation and Characterization of an Adult Stem Cell Population from Human Epidural Fat
Table 1
A summary for MSCs, bipotent cells, and unipotent cells that have been identified from 10 patients. Based on qPCR, histology, and flow cytometry data.
| | Age | Sex | Cell potency | Cell surface marker expression (percent of positive cells) | Chondrogenic differentiation capacity | Osteogenic differentiation capacity | Adipogenic differentiation capacity | Passage number of cells at time of testing | ~Population doublings of cells at time of testing | | CD271 | CD105 | CD90 | CD73 | CD44 |
| | 55 | M | MSCs (2/10 patients) | 5% | 29% | 85% | 100% | 100% | Positive | Positive | Positive | 4 | 6.78 | | 70 | M | <1% | 19% | 79% | 95% | 100% | Positive | Positive | Positive | 4 | 7.26 |
| | 66 | F | Bipotent progenitors (6/10 patients) | <1% | 73% | 97% | 100% | 100% | Negative | Positive | Positive | 4 | 5.38 | | 64 | M | <1% | 95% | 99% | 100% | 100% | Negative | Positive | Positive | 4 | 7.35 | | 47 | M | 5% | 24% | 75% | 74% | 75% | Negative | Positive | Positive | 4 | 7.55 | | 60 | F | 5% | 55% | 99% | 100% | 100% | Negative | Positive | Positive | 4 | 8.36 | | 24 | F | 4% | 30% | 99% | 100% | 100% | Negative | Positive | Positive | 4 | 8.11 | | 80 | M | 15% | 55% | 99% | 100% | 100% | Positive | Positive | Negative | 4 | 7.08 |
| | 67 | F | Unipotent progenitors (2/10 patients) | 5% | 29% | 74% | 75% | 75% | Negative | Negative | Positive | 4 | 7.75 | | 73 | F | 7% | 23% | 100% | 100% | 100% | Negative | Negative | Positive | 4 | 7.26 |
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