Research Article
Characteristics of Intestinal Microecology during Mesenchymal Stem Cell-Based Therapy for Mouse Acute Liver Injury
Figure 5
MSC transplantation improves intestinal histopathology and epithelial tight junctions (TJs). (a) Histopathology of the ileum of different experimental groups. (b) Relative expression of zonula occludens- (ZO-) 1 mRNA by real-time quantitative polymerase chain reaction. per group; ; -test (). (c) Immunofluorescence analysis of ZO-1 distribution. (d) Ultrastructure of TJs using transmission electron microscopy. Oil: olive oil control; c: CCl4-treated group; m: MSC-transplanted group. 48 h, 1 w, and 2 w indicate 48 hours, 1 week, and 2 weeks after CCl4 treatment, respectively.
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