Characteristics of Intestinal Microecology during Mesenchymal Stem Cell-Based Therapy for Mouse Acute Liver Injury

Table 1

Number of sequences and operational taxonomic units, good coverage estimation, and diversity index for each group from the pyrosequencing analysis.

Group	No. of reads	No. of OTUs	Good coverage	Richness indices				Alpha diversity
				Chao1	95% CI	Observed species	95% CI	Shannon	Simpson
Oil	319,780	586	99.78%	353	270.7–434.4	264	218–309	5.143298	0.928244
c48h	291,936	656	99.78%	348	291.3–404.3	280	256–304	4.973242	0.933629
c1w	314,004	896	99.77%	386	251.7-520.5	324	177-470	5.308093	0.936644
c2w	313,643	794	99.76%	409	319.0-498.2	335	269-400	5.811608	0.952789
m48h	347,219	713	99.70%	460	339.3-580.5	374	276-472	5.381068	0.927921
m1w	273,154	596	99.78%	342	269.2-415.4	265	233-296	5.546923	0.947188
m2w	272,850	668	99.78%	364	228.8-499.3	289	220-358	5.763545	0.960001

Oil: olive oil control; c: carbon tetrachloride- (CCl₄-) treated group; m: mesenchymal stem cell- (MSC-) transplanted group. 48 h, 1 w, and 2 w indicate 48 h, 1 week, and 2 weeks following CCl₄ treatment, respectively. per group. Sequences were clustered into operational taxonomic units (OTUs) based on 97% sequence similarity.