Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition

Figure 4

Effects of MSCs on α-SMA, Col I, FN, laminin β, nephrin, and synaptopodin mRNA expression in kidney tissue measured by real-time PCR. , , and . The α-SMA, Col I, FN, and laminin β levels were obviously higher in PBS group than in the other three groups, and Col I level was lower in the SHED and BMSCs groups than in the PBS group. Nephrin and synaptopodin were lower in the PBS group than in the other three groups.