In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic Heart Disease

Figure 4

T2 images. T2 images from one representative patient. Images a1, b1, and c1 show the longitudinal position of respective short-axis images (green lines). Images a2–a6, b2–b6, and c2–c6 show serial short-axis images at the same three longitudinal positions (a, b, c) at baseline, day 0, day 1, day 3, and day 7 after injection. The yellow arrows point to hypointense areas in the images suspected to point out injected USPIO-labeled MSCs (slice thickness 5 mm). USPIO = ultrasmall paramagnetic iron oxide; MSC = mesenchymal stromal cell.