Identification of Aberrantly Expressed Genes during Aging in Rat Nucleus Pulposus Cells

Table 5

List of top 5 terms of down regulated genes enriched by GO and KEGG analysis.

Terms	Count	-log10 ( value)
KEGG:rno04512:ECM-receptor interaction	12	6.305467082
KEGG:rno04510:Focal adhesion	16	5.283730936
KEGG:rno04151:PI3K-Akt signaling pathway	18	3.918980827
KEGG:rno04974:Protein digestion and absorption	8	2.964674869
KEGG:rno04024:cAMP signaling pathway	11	2.565239027
GO BP:0007155~cell adhesion	19	5.677119186
GO BP:0035987~endodermal cell differentiation	6	3.820807813
GO BP:0001503~ossification	9	3.307311242
GO BP:0007160~cell-matrix adhesion	8	3.272206365
GO BP:0010628~positive regulation of gene expression	17	2.767181699
GO MF:0005201~extracellular matrix structural constituent	7	3.709602001
GO MF:0005509~calcium ion binding	28	3.596212048
GO MF:0003735~structural constituent of ribosome	18	2.633105261
GO MF:0044325~ion channel binding	9	2.592276912
GO MF:0005178~integrin binding	8	2.584636716
GO CC:0031012~extracellular matrix	28	12.71649934
GO CC:0005604~basement membrane	16	9.863156842
GO CC:0005615~extracellular space	53	6.939058168
GO CC:0005578~proteinaceous extracellular matrix	20	6.645158563
GO CC:0005925~focal adhesion	25	6.484468766