Mesenchymal Stem Cells Exhibit Both a Proinflammatory and Anti-Inflammatory Effect on Saccular Aneurysm Formation in a Rabbit Model

Figure 4

Cytokine and MMP serum concentrations in the control and experimental groups on days 1, 15, and 29 (). (a) MCP-1α, (b) MIP-1α, (c) MIP-2, (d) IL-1β, (e) IL-10, (f) TNF-α, (g) MMP-2, (h) proMMP-9, and (i) VEGF. Within-subject analyses revealed no statistically significant differences in the control group cytokine/MMP levels over 29 days, but a significant increase in MIP-2, IL-10, and proMMP-9 on day 29, with a significant decrease in MMP-2 on day 29. Red values show significant findings on between-subject analyses.

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