Review Article

Meta-Analysis and Evidence Base for the Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells in Knee Cartilage Repair: Methodological Guidelines and Quality Assessment

Table 1


CharacteristicsNo. of studiesReferences

Follow-up duration
0-6 months2[23, 35]
7-12 months11[28, 29, 34, 41, 42, 4446, 48, 55]
13-24 months8[30, 32, 41, 47, 5052, 62]
Up to 36 months3[25, 26, 38]
Over 3 years6[31, 33, 3537, 39]
Cellular dose
Less than 10 million7[24, 27, 36, 41, 45, 52, 55]
10-20 million5[27, 29, 50, 51, 56]
More than 20 million6[23, 29, 44, 4648]