Mesenchymal Stem Cells for Liver Regeneration in Liver Failure: From Experimental Models to Clinical Trials

Figure 1

Histological images of a normal rat (a) and long-term cholestatic (b) liver parenchyma. Note the severe epithelial bile cell proliferation associated with fibrosis and hepatocyte death by necrosis and apoptosis in (b). V: portal vein, A: hepatic artery, B: biliary duct, and H: hepatocytes.

(a)

(b)