Phage-Based Artificial Niche: The Recent Progress and Future Opportunities in Stem Cell Therapy

Figure 3

Phage engineering examples of artificial stem cell niches. Engineered nanofibrous structured phage to express short functional peptides has been utilized as tissue engineering scaffold imitating the ECM fibrous protein network for various tissue engineering purposes. The peptides displayed on the arrow are the peptide displayed on the engineered phage for providing various cues to the stem/progenitor cells to mimic a native stem cell niche. Adapted from [131, 132, 144, 146, 148, 149].