Strontium Promotes the Proliferation and Osteogenic Differentiation of Human Placental Decidual Basalis- and Bone Marrow-Derived MSCs in a Dose-Dependent Manner

Figure 5

Effect of strontium on the osteogenic differentiation of BM- and PDB-MSCs cultured in the osteogenic medium. (a) ALP staining of BM- and PDB-MSCs cultured with strontium for 7 days. Red indicates positive staining. Scale bar: 100 μm. (b) ALP activity of BM- and PDB-MSCs treated with strontium for 7 days. for each group. (c) Osteogenic gene expression of BM- and PDB-MSCs on days 3, 7, and 14. for each group. (d) Alizarin red staining of BM- and PDB-MSCs after 21 days of culture. Red indicates the mineralization of the extracellular matrix. All of these results are representative of three independent experiments. when compared with the OST group; ^# when compared with the OST group. OST: osteogenic medium.

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