Mesenchymal Stromal Cells from the Epidermis and Dermis of Psoriasis Patients: Morphology, Immunophenotype, Differentiation Patterns, and Regulation of T Cell Proliferation

Figure 2

Morphology and proliferation of the MSCs obtained. (a) Representative photos of the cell morphology observed in each sample are shown (100x, ), along with representative images of cells with a spindle-shaped or large morphology (400x, ). (b) The of the percentage of spindle-shaped cells and large cells in the MSC cultures. Statistically significant differences between NLE-MSCs vs. HD-, NLD-, LD-, HE-, and LE-MSCs. ^§Statistically significant differences between BM-MSCs vs. HD-, NLD-, LD-, HE-, and LE-MSCs. (c) Cell proliferation (fold change) was measured after 100,000 cells were cultured for 6 days. After culture, the cells were harvested and counted using trypan blue staining; the viability percentage in all cultures was greater than 98%. Statistically significant differences with . ^§Statistically significant differences with between BM-MSCs vs. HD-, NLD-, LD-, and HE-MSCs.

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