A Potential Antitumor Effect of Dendritic Cells Fused with Cancer Stem Cells in Hepatocellular Carcinoma

Figure 3

Flow cytometry analysis of expression change of surface molecules on immature DCs, mDCs, and fusion DCs and the immunological function of fusion cells. (a) The expression change of the costimulatory molecule and mature molecule on the cell surface of different DCs. , , value (the same as the first group). (b) The IL-12p70 level after 24 h culture in the supernatants from the four groups. , . (c) The different proliferation indices of the DCDC group, mDC group, HepG2/DC group, and CD90⁺HepG2/DC group. , , . (d) IFN-γ ELISpot analysis of T cell IFN-γ secretion induced by the four groups of DCs. , .

(a)

(b)

(c)

(d)