Endometriotic Peritoneal Fluid Promotes Myofibroblast Differentiation of Endometrial Mesenchymal Stem Cells

Figure 1

Ectopic endometria exhibit enhanced expression of fibrotic proteins and fibrosis degree. (a) The expression of collagen I, α-SMA, fibronectin, and CTGF in human endometriotic or endometrial tissues from 32 women with endometriosis and 20 women without endometriosis was detected by immunohistochemistry (×200) and quantified by Image ProPlus. versus the normal endometria. versus the normal endometria. versus the paired eutopic endometria from the same patients with endometriosis. (b) The collagen deposits in the endometriotic or endometrial tissues were detected by Masson trichrome staining (×200). EMs represent endometriosis. (c) Relative extent of fibrosis was determined by quantifying the Masson trichrome staining by Image ProPlus. versus the normal endometria. versus the normal endometria. versus the paired eutopic endometria from the same patients with endometriosis (A). versus the ectopic endometria from patients with stage I/II endometriosis (B).

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