Stem Cells International / 2019 / Article / Fig 2

Research Article

Mitochondrial Fusion by M1 Promotes Embryoid Body Cardiac Differentiation of Human Pluripotent Stem Cells

Figure 2

Gene expression of human iPSCs (iPSC-Foreskin-2 cell line) treated with M1 in differentiation medium. (a–d) mRNA of mesodermal cardiac transcription factors (a), pluripotency markers (b), mitochondrial fission and fusion markers (c), and cell proliferation markers (d) in human PSCs treated with either DMSO vehicle control (control) or M1 at 5 or 10 μM in RPMI+B-27 medium for 48 hours. . Data are expressed as . vs. control by one-way paired ANOVA with Dunnett’s post hoc test.

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