Emerging Role of Mesenchymal Stromal Cell-Derived Extracellular Vesicles in Pathogenesis of Haematological Malignancies

Figure 1

Schematic representation of the bone marrow (BM) microenvironment architecture and BM resident cell crosstalk via extracellular vesicles (exosomes and microvesicles) released from multipotent mesenchymal stromal cells (MSC). EC: endothelial cells; HPC: haematopoietic progenitor cells; HSC: haematopoietic stem cells.