A Noninvasive Imaging Toolbox Indicates Limited Therapeutic Potential of Conditionally Activated Macrophages in a Mouse Model of Multiple Organ Dysfunction

Figure 6

All mice received 10⁷ primary bone marrow-derived macrophages which expressed luciferase via tail vein administration. Whole-body images of typical mice treated with either saline or adriamycin on both days 1 (a) and 4 (b). Ex vivo bioluminescence images from typical saline (c, e) and adriamycin- (d, f) treated mice on both days 1 (c, d) and 4 (e, f). Individual scales are shown on the right of each image. Each image shows the liver, kidneys, heart, lungs, and spleen from an individual mouse. Scales for all ex vivo images are identical, as are scales for all whole-body images.

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