Intestinal Organoids as a Novel Complementary Model to Dissect Inflammatory Bowel Disease

Figure 1

(a) Reprogramming of somatic cells towards induced pluripotent stem cells (iPSCs) and differentiation of iPSC into intestinal organoids using different culture conditions. (b) Immunofluorescence staining of induced human intestinal organoids for essential markers of intestinal differentiation. After evolution through the protocol shown in (a), organoids express mucin, claudin 1, and lysozyme together with E-cadherin.

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