Human Amnion Epithelial Cell Therapy for Chronic Liver Disease

Figure 5

Mechanisms that contribute to the loss or gain of liver parenchyma during CLD. Liver repair following injury involves a balancing act between mechanisms that result in either loss or gain of the liver parenchyma. Accordingly, the progression of CLD can be framed as liver repair that favours parenchyma loss over gain. Flipping this balance in favour of parenchyma gain is the ultimate goal of regenerative therapies for CLD.