Review Article

Unchain My Heart: Integrins at the Basis of iPSC Cardiomyocyte Differentiation

Figure 3

Engineered materials supporting in vitro modelling. Integrin-mediated pathways relevant for iPSC cardiac differentiation can be enhanced in vitro by the use of ad hoc-designed biomaterials. Toward this aim, chemical, geometrical, mechanical, and physical properties of the substrates are relevant.