Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats

<div>Transwell migration assay of MSCs. (a) Migration of MSCs treated with NPC exosomes at the concentration of 25 <i>μ</i>g/ml, 50 <i>μ</i>g/ml, 75 <i>μ</i>g/ml, and 100 <i>μ</i>g/ml was observed under the microscope (x200). (b) Numbers of migrated MSCs at the concentration of 25 <i>μ</i>g/ml, 50 <i>μ</i>g/ml, 75 <i>μ</i>g/ml, and 100 <i>μ</i>g/ml. 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Stem Cells International

fig6

Figure 6

Figure 6: Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats 

Figure 6 | Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats 