Clinical Study

Safety and Feasibility of Repeated Intrathecal Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells in Patients with Neurological Diseases

Table 9

Comparison of adverse events between our study and previous studies of intrathecal non-MSCs stem cells.

Adverse events (person-time)Total (%)
Our study (%)
Literature review (%)

Headache114 (8.21)3 (2.05)111 (8.94)0.007
Dizziness2 (0.14)2 (1.37)0 (0.00)0.011
Fever114 (8.21)5 (3.42)109 (8.78)0.026
Nausea20 (1.44)2 (1.37)18 (1.45)1.000
Pain at puncture site32 (2.30)6 (4.11)26 (2.10)0.125
Neck pain1 (0.07)1 (0.68)0 (0.00)0.105