Identification of WNT16 as a Predictable Biomarker for Accelerated Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells <i>In Vitro</i>

<div>Expression of markers in a heterogeneous population of progenitors. (a) Expression of the six selected genes (WNT16, DPP4, DCLK1, IGFBP5, FBLN2, and HIGD1A) was confirmed in ND and OP clones as well as T-MSCs from four different donors using real-time quantitative PCR. 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330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,49.709,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg>).</span> (b) Correlation between WNT16 and DCLK1 expression in undifferentiated cells and the degree of osteogenic differentiation as determined by matrix mineralization among T-MSCs from 10 different donors. (c) Representative images showing the degree of matrix mineralization and WNT16 and DCLK1 expression examined by RT-PCR.</div>

Stem Cells International

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Figure 4

Figure 4: Identification of WNT16 as a Predictable Biomarker for Accelerated Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells <i>In Vitro</i> 

Figure 4 | Identification of WNT16 as a Predictable Biomarker for Accelerated Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells In Vitro 