Protection of the Peritoneal Membrane by Peritoneal Dialysis Effluent-Derived Mesenchymal Stromal Cells in a Rat Model of Chronic Peritoneal Dialysis

Figure 6

Incubation with pMSC-CM inhibits the expression of NOS2 in activated THP1 cells. PMA/LPS-activated THP1 cells were incubated in the absence or presence of 50% pMSC-CM (/) for 24 h, while unactivated cells were used as the medium control. (a) NO production in THP1 cell cultures in each group. Data were presented as of four determinants and were statistically analyzed using the two-tailed -test. (PMA/LPS vs. medium), (PMA/LPS+50% vs. PMA/LPS), and (PMA/LPS+50% vs. medium). (b) Western blot analysis of cellular NOS2 protein expression in each group. Data represented a typical Western blot of NOS2 protein of three separate examinations. RU: ratio unit of NOS2 to GAPDH.

(a)

(b)