Research Article

Isolation, Characterization, and Safety Evaluation of Human Skin-Derived Precursors from an Adherent Monolayer Culture System

Table 2

List of major transcription factors with strong evidence involved in the transculturing process ().

FunctionUpregulated transcription factorDownregulated transcription factor

DNA bindingSnail2, Pou2f2, Foxc1, Nfkb2, Bach2, Foxo3, Nr1d1, Creg1, Foxo1, Nr4a2, Klf10, Tg1f1Meox2, Foxm1, Klf7, Meis2, Mitf
TransactivationFoxc1, Rora, Foxo3, Foxo1, Nr4a2, Tg1f1Meox2, Klf7, Meis2, Aff3, Cited2, Mitf
TF PPINfkbia, Bag1Bag1, Fhl2, Hmgb2, Cited2
CoactivationNcoa7, Nr4a2Cited2
Other/Id1