Pancreatic Progenitors and Organoids as a Prerequisite to Model Pancreatic Diseases and Cancer

Figure 2

Schematic outline of endocrine lineage commitment in vitro. Overview of stepwise and stage-specific modulation of cellular signaling pathways during in vitro differentiation summarizing the main protocols. For each pancreatic lineage, specific transcription factors and cellular markers are shown. According to the Nostro protocol [17].