Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering

Figure 1

The whole experimental process. CV-MSCs were treated with HP or non-HP for 24 h, then the pretreated CV-MSCs were transferred to a simulated ischemic environment for another 24 h. The survival and secretion of CV-MSC were determined. The effects of condition media obtained from CV-MSCs after ischemic stimulus on EC proliferation, migration, and differentiation were evaluated.