Gestational Tissue-Derived Human Mesenchymal Stem Cells Use Distinct Combinations of Bioactive Molecules to Suppress the Proliferation of Human Hepatoblastoma and Colorectal Cancer Cells

Figure 3

Effects of hMSC-derived bioactive molecules on the proliferation of Saos2, A549, and U251 cells. Graphs show the growth kinetics of osteosarcoma cell Saos2 (a), lung adenocarcinoma cell A549 (b), and glioma cell U251 (c), which were cultured in conditioned medium derived from various normal and cancer-associated hMSC-conditioned media for 7 days. The growth kinetics of cancer cells were determined by the xCELLigence real-time cell analyzer and were reported as the cell index against culture time. Saos2, A549 and U251 cells cultured in DMEM supplemented with 10% () FBS serve as controls. Data are presented as the of three independent experiments.

(a) Osteosarcoma cell Saos2

(b) Lung cancer cell A549

(c) Glioma cell U251