Safety and Localization of Mesenchymal Stromal Cells Derived from Human Adipose Tissue-Associated Hyaluronic Acid: A Preclinical Study

Table 2

Assessment of body-weight change in test systems followed up for six weeks after subcutaneous infusion of test substances.

Weeks	Body weight (g)
	Groups	Saline (NaCl)		ACS		HA 1%		ASC + HA 1%		FAC
	Animals ()	Media	SD	Media	SD	Media	SD	Media	SD	Media	SD
1	5	295	31	341	63	340	27	343	27	362	25
2	5	328	39	354	43	348	22	360	30	370	31
3	5	353	42	370	38	351	24	375	26	380	31
4	5	366	39	384	27	360	23	385	28	392	35
5	5	381	44	399	22	374	22	387	22	391	33
6	5	390	47	407	16	380	21	404	25	407	38

: no. of animals; NaCl: sodium chloride; HA: hyaluronic acid; ASC: adipose-derived stromal cells; FAC: Freund’s adjuvant complete. ASC+HA 1%. ANOVA with Bonferroni’s correction (Bonferroni’s post hoc test).