Research Article
Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2/TLR4 Signaling Pathway
Figure 3
AMSC-derived exosomes prevent brain damage in CPB rats. SPF SD male rats were randomly divided into four groups including the sham operation group (sham group); CPB surgery group (CPB group); exosome+CPB group (EXO group); and exosome+CPB group+TLR2/TLR4 agonist group (TLR group) with 10 rats in each group. (a) H&E staining revealed the damage of hippocampus tissues in each group (scale ). (b) Brain injury markers (NSE and S100-β) in serum in each group; ().
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