Hypoxia Promotes Vascular Smooth Muscle Cell (VSMC) Differentiation of Adipose-Derived Stem Cell (ADSC) by Regulating Mettl3 and Paracrine Factors

Figure 2

Differentiation of ADSCs and expression of m6A methyltransferase and demethylases. (a) Photomicrographs of the VSMC differentiation from ADSCs at 0, 7, 14, and 21 days. (b) The expression level of mRNA and protein of Alkbh5, Fto, and Mettl3 in ADSCs after 7 and 14 days of induction. (c) The expression of a protein level of 4 VSMC-specific markers after 7 and 14 days of induction.

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