Hypoxia Promotes Vascular Smooth Muscle Cell (VSMC) Differentiation of Adipose-Derived Stem Cell (ADSC) by Regulating Mettl3 and Paracrine Factors

<div>Hypoxia promotes VSMC differentiation form ADSCs by upregulating the expression of Mettl3. (a) Hypoxia promotes the ADSC differentiate into VSMCs. (b) The mRNA and protein levels of Mettl3 were increased under hypoxia condition. (c) The mRNA levels of <i>α</i>-SMA, SM22<i>α</i>, calponin, and SM-MHC were increased under hypoxia condition. 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Stem Cells International

fig4

Figure 4

Figure 4: Hypoxia Promotes Vascular Smooth Muscle Cell (VSMC) Differentiation of Adipose-Derived Stem Cell (ADSC) by Regulating Mettl3 and Paracrine Factors 

Figure 4 | Hypoxia Promotes Vascular Smooth Muscle Cell (VSMC) Differentiation of Adipose-Derived Stem Cell (ADSC) by Regulating Mettl3 and Paracrine Factors 