Research Article

Mesenchymal Stem Cell Therapy Using Human Umbilical Cord in a Rat Model of Autoimmune-Induced Premature Ovarian Failure

Figure 4

Ovarian histopathology using H&E staining. (a) Healthy rat ovarian. Photographs in differently colored individual square boxes marked in (a) were enlarged and marked with a-1, a-2, and a-3. Pr: primordial follicle; Pm: primary follicle; Sf: secondary follicle; Af: antral follicle; Oo: oocyte; Gc: granulosa cell. (b) Histopathologic examination of ovary tissues after ovarian antigen injection. (c) Rat ovary in the group of blank controls. (d) Rat ovary in the group of solvent controls. (e–g) Histopathologic examination of ovarian tissues after UCMSC transplantation. (e) Low-dose group. (f) Medium-dose group. (g) High-dose group. .