Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study

Figure 1

Pathophysiological variants of case scenario in tissue repair after injury. The best case scenario for wound healing is tissue regeneration—the complete repair of structure and function. Adults usually experience wound healing with various degrees of scar formation. Tissue repair does not occur if chronic inflammation develops. The strategy to control the inflammatory response is a shift in the balance from chronic inflammation toward tissue regeneration.