Three Growth Factors Induce Proliferation and Differentiation of Neural Precursor Cells In Vitro and Support Cell-Transplantation after Spinal Cord Injury In Vivo

<div>Differentiation of transplanted NPCs in vivo 8 weeks after cervical SCI. (a) Spinal cord cross-section showing the spatial distribution of surviving NPCs (GFP+/DAPI+), NPC-derived neurons (GFP+/DAPI+/NeuN+) and NPC-derived oligodendrocytes (GFP+/DAPI+/APC+). (b) Number of NPC-derived neuronal precursors (DCX+/GFP+) and mature neurons (NeuN+/GFP+) as well as oligodendrocyte precursors (NG2+/GFP+) and mature oligodendrocytes (APC+/GFP+) in the injured spinal cord of animals in the NPC group (group 1).</div>

Stem Cells International

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Figure 5: Three Growth Factors Induce Proliferation and Differentiation of Neural Precursor Cells In Vitro and Support Cell-Transplantation after Spinal Cord Injury In Vivo

Figure 5 | Three Growth Factors Induce Proliferation and Differentiation of Neural Precursor Cells In Vitro and Support Cell-Transplantation after Spinal Cord Injury In Vivo 