Stem Cells International / 2020 / Article / Fig 4

Research Article

Screening and Functional Pathway Analysis of Pulmonary Genes Associated with Suppression of Allergic Airway Inflammation by Adipose Stem Cell-Derived Extracellular Vesicles

Figure 4

Effects of ASC-derived EVs on PON1, Bex2, Igfbp6, Fpr1, and Scgb1c1 gene expression. PON1 and Scgb1c1 gene expression was significantly decreased in the OVA group compared to the CON group. However, EV treatment markedly increased the expression of PON1, Bex2, Igfbp6, and Scgb1c1 in asthmatic mice. ; ; §; ; . ASCs: adipose stem cells; Bex2: brain-expressed X-linked 2; CON: control; EV: extracellular vesicle; Fpr1: formyl peptide receptor 1; Igfbp6: insulin-like growth factor binding protein 6; OVA: ovalbumin; PON1: paraoxonase 1; Scgb1c1: secretoglobin family 1C member 1.

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